Peptide Database

Peptide NameTCTP-CPP 23

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC72H114N20O14

DescriptionStandard

        WIIFRIAATHKK
    

Molecular Weight1483.80 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.2371

GRAVY Index0.23

Hydrophobic Moment 0.45

Boman Index0.12

Instability Index28.90

Aliphatic Index 114.17

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 562.06

LogP -1.26

H-bond Donors 21.0

H-bond Acceptors 18.0

Rotatable Bonds 48.0

Heavy Atoms 106.0

Ring Count 4.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312449 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFITC

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. Eur J Pharm Sci. 2011 May 18;43(1-2):25-31. doi: 10.1016/j.ejps.2011.03.007. PMID: 21440624. PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/

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