Peptide Database

Peptide NameAla54 substitution mutant of Tat (49-57)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC51H103N29O10

DescriptionStandard

        RKKRRARRR
    

Molecular Weight1282.55 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.8620

GRAVY Index-3.67

Hydrophobic Moment 0.68

Boman Index-1.95

Instability Index236.04

Aliphatic Index 11.11

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 719.56

LogP -8.87

H-bond Donors 30.0

H-bond Acceptors 18.0

Rotatable Bonds 49.0

Heavy Atoms 90.0

Ring Count 0.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424217 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Termfluorescein with 6-aminohexanoic acid (Ahx) spacer

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

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