Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC148H222N38O43S3

DescriptionStandard

        ASSQHLCGSHLVDALYMVCGEKGFFYQPKT
    

Molecular Weight3317.77 Da

Isoelectric Point (pI)6.94

Net Charge (pH 7.0)-0.05

Net Charge (pH 7.4) -0.38

Charge Density (pH 7.0) -0.0017

GRAVY Index-0.03

Hydrophobic Moment 0.37

Boman Index0.15

Instability Index44.09

Aliphatic Index 65.00

Aromaticity 0.1333

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1289.99

LogP -12.24

H-bond Donors 46.0

H-bond Acceptors 48.0

Rotatable Bonds 106.0

Heavy Atoms 232.0

Ring Count 7.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198328 VERIFIED: YES

Provenance & Taxonomy

OrganismPantodon buchholzi [Animal]

FamilyInsulin

Tax ID8276

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0343741 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0412617 VERIFIED: NO

Provenance & Taxonomy

OrganismPantodon buchholzi [Animal]

FamilyInsulin

Tax ID8276

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic