Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC731H1148N188O218S8

DescriptionStandard

        MTISLTTFIPIQISDNSPWFLHISLALYPNTYSGWSESKCWKNDLGHCRRRCLDDERYIRLCKSKVSCCIPITSSPVYTLKPLPPLFHLENITIDLSELTPFPLSPMSGINDAVTFNENKITESPNTLTVSSQSVPSPSRIPLVD
    

Molecular Weight16314.58 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.77

Charge Density (pH 7.0) -0.0088

GRAVY Index-0.12

Hydrophobic Moment 0.57

Boman Index0.07

Instability Index69.14

Aliphatic Index 91.38

Aromaticity 0.0828

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6426.88

LogP -64.01

H-bond Donors 226.0

H-bond Acceptors 228.0

Rotatable Bonds 514.0

Heavy Atoms 1145.0

Ring Count 33.0

Amide Bonds 154.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172136 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Tax ID51338

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal