Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC375H577N91O100S11

DescriptionStandard

        MKIFYYLLHFFCYMTFILPAICTLVDPERCSKMYGQCRTRCYKIEKQIDICYSPSKICCIQRAFEEDLS
    

Molecular Weight8312.86 Da

Isoelectric Point (pI)8.12

Net Charge (pH 7.0)1.51

Net Charge (pH 7.4) 1.10

Charge Density (pH 7.0) 0.0219

GRAVY Index0.12

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index64.66

Aliphatic Index 80.58

Aromaticity 0.1594

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3075.49

LogP -19.13

H-bond Donors 116.0

H-bond Acceptors 114.0

Rotatable Bonds 272.0

Heavy Atoms 577.0

Ring Count 15.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0193515 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence