Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC428H725N127O120S8

DescriptionStandard

        MLLDHSSSLSGHIKILFLAVAVLVVLDQASPDGWTRKCGYGTGNCRKHCKKSEKKKEKCGLRKLCCIPIKHKSSKLVRKEETSKLSMN
    

Molecular Weight9826.63 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)11.79

Net Charge (pH 7.4) 11.25

Charge Density (pH 7.0) 0.1340

GRAVY Index-0.39

Hydrophobic Moment 0.58

Boman Index-0.13

Instability Index26.97

Aliphatic Index 86.36

Aromaticity 0.0341

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4019.44

LogP -40.78

H-bond Donors 149.0

H-bond Acceptors 144.0

Rotatable Bonds 348.0

Heavy Atoms 683.0

Ring Count 10.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343820 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyDefensin

Tax ID30522

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0422961 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin