Peptide Database

Peptide NamekEA2x3

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC108H186N48O32S3

DescriptionStandard

        ARRRCSDRFRNCPADEALCGRRR
    

Molecular Weight2765.13 Da

Isoelectric Point (pI)11.16

Net Charge (pH 7.0)4.77

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.2074

GRAVY Index-1.45

Hydrophobic Moment 0.66

Boman Index-0.79

Instability Index123.07

Aliphatic Index 30.00

Aromaticity 0.0435

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1365.15

LogP -18.87

H-bond Donors 55.0

H-bond Acceptors 40.0

Rotatable Bonds 93.0

Heavy Atoms 191.0

Ring Count 2.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321139 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilykEA2x3

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery