Peptide Database

Peptide NameBrentuximab vedotin

Function Ontology

Anticancer

Antiviral

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC193H299N47O57S

DescriptionStandard

        QIQLQQSGPEVVKPGASVKISCKASGYTFTDYYITWVK
    

Molecular Weight4221.78 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.52

Charge Density (pH 7.0) 0.0460

GRAVY Index-0.21

Hydrophobic Moment 0.53

Boman Index0.09

Instability Index35.21

Aliphatic Index 76.84

Aromaticity 0.1316

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1691.57

LogP -16.14

H-bond Donors 59.0

H-bond Acceptors 60.0

Rotatable Bonds 136.0

Heavy Atoms 298.0

Ring Count 8.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165129 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10090

Structure & Mods

Configcyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Anticancer

Half-LifeTerminal half-life is 4-6 days