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MYP_089586
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Basic Information
Brevinin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
24 amino acids
C126H203N31O27S2
Standard
Sequence
FFPLIAGLAANFLPQILCKIARKC
Physicochemical Analysis
2648.28 Da
9.50
2.74
2.50
0.1141
1.10
0.74
0.36
31.88
130.42
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
915.16
-3.16
32.0
32.0
84.0
186.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029246 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0090587 VERIFIED: YES
Provenance & Taxonomy
Rana grahami [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01907
RECORD: Rec_0124167 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial
PaperX. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0172288 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0188380 VERIFIED: NO
Provenance & Taxonomy
Odorrana andersonii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial