Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC884H1401N261O264S11

DescriptionStandard

        MKKRIIACSTAAIISLAATLWPQALRTSPEAQQKMAKYEDCRKTPYYCPAGVLTVGIGSTSKVEDRQYAEGEIAERWVNDLMRAEKCTNREFNGAAAPQKVFESMTDGTFNVGCTGLGWYTNGKGQKVRTTLWRHAQAGNWKGVCERLTDFVNSAGKRSQGLVNRRTDFQAWCLSDPALKGAK
    

Molecular Weight20261.89 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)9.54

Net Charge (pH 7.4) 9.12

Charge Density (pH 7.0) 0.0521

GRAVY Index-0.51

Hydrophobic Moment 0.83

Boman Index-0.08

Instability Index40.98

Aliphatic Index 63.55

Aromaticity 0.0874

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8552.48

LogP -101.35

H-bond Donors 308.0

H-bond Acceptors 286.0

Rotatable Bonds 675.0

Heavy Atoms 1420.0

Ring Count 29.0

Amide Bonds 199.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0348547 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella michiganensis [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence