Peptide Database

Peptide NameCecropin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC193H322N62O48

DescriptionStandard

        RWKPFKKLEKVGRNIRNGIIRYNGPAVAVIGQATSIAR
    

Molecular Weight4279.01 Da

Isoelectric Point (pI)11.85

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.2042

GRAVY Index-0.40

Hydrophobic Moment 0.85

Boman Index-0.12

Instability Index28.23

Aliphatic Index 95.00

Aromaticity 0.0789

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1822.16

LogP -16.93

H-bond Donors 65.0

H-bond Acceptors 56.0

Rotatable Bonds 144.0

Heavy Atoms 303.0

Ring Count 6.0

Amide Bonds 41.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0172991 VERIFIED: YES

Provenance & Taxonomy

OrganismPlutella xylostella [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)