Peptide Database

Peptide NameSLAY-screened peptide P3903

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC106H165N23O27S

DescriptionStandard

        PLTLSVTLLNKFMSGFALSW
    

Molecular Weight2225.65 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)0.96

Net Charge (pH 7.4) 0.90

Charge Density (pH 7.0) 0.0479

GRAVY Index0.92

Hydrophobic Moment 0.50

Boman Index0.43

Instability Index39.06

Aliphatic Index 117.00

Aromaticity 0.1500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 788.28

LogP -4.72

H-bond Donors 29.0

H-bond Acceptors 29.0

Rotatable Bonds 70.0

Heavy Atoms 157.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153412 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/