Peptide Database

Peptide NamePore-forming peptide ameobapore B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC469H767N121O132S7

DescriptionStandard

        MRAIIFVLIFAIAFAATREGAILCNLCKDTVKLVENLLTVDGAQAVRQYIDNLCGKASGFLGTLCEKILSFGVDELVKLIENHVDPVVVCEKIHAC
    

Molecular Weight10437.29 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-2.37

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0247

GRAVY Index0.72

Hydrophobic Moment 0.66

Boman Index0.24

Instability Index12.85

Aliphatic Index 128.96

Aromaticity 0.0625

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4028.66

LogP -29.78

H-bond Donors 143.0

H-bond Acceptors 139.0

Rotatable Bonds 352.0

Heavy Atoms 729.0

Ring Count 9.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399836 VERIFIED: NO

Provenance & Taxonomy

OrganismEntamoeba histolytica [Protist]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Antiparasitic Cytolytic Non-hemolytic Non-ribosomal

MethodQualitative functional evidence