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MYP_089402
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Basic Information
Cyanophlyctin (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C108H183N31O27
Standard
Sequence
FLNALKNFAKTAGKRLKSLLN
Physicochemical Analysis
2347.80 Da
11.33
4.76
4.55
0.2265
-0.12
0.66
-0.05
5.76
107.14
0.0952
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
981.03
-8.72
34.0
32.0
83.0
166.0
2.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149467 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Micrococcus luteus PTCC1625
4.7 μM
MIC
PaperIdentification and Characterization of Novel Antibacterial Peptides from Skin Secretions of Euphlyctis cyanophlyctis
RECORD: Rec_0210086 VERIFIED: NO
Provenance & Taxonomy
Indean skipper [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0212181 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli HP101BA 7601c
6.4 μM
MIC
PaperIdentification and Characterization of Novel Antibacterial Peptides from Skin Secretions of Euphlyctis cyanophlyctis
RECORD: Rec_0222015 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01834
RECORD: Rec_0242510 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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