Peptide Database

Peptide NameAgalsidase beta

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1312H1937N345O388S20

DescriptionStandard

        LDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMAL
    

Molecular Weight29391.79 Da

Isoelectric Point (pI)4.62

Net Charge (pH 7.0)-14.86

Net Charge (pH 7.4) -15.54

Charge Density (pH 7.0) -0.0583

GRAVY Index-0.43

Hydrophobic Moment 0.74

Boman Index0.03

Instability Index32.63

Aliphatic Index 68.12

Aromaticity 0.1373

Extinction Coeff. Reduced 83880.00

Extinction Coeff. Oxidized 84505.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0259287 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Cricetulus griseus [Animal]

FamilyEnzyme

Tax ID9606;10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme replacement

Half-Life45-102 min