MYP_089364
Unnamed
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Immunology
▸
Innate immune defense
▸
Host defense peptide
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Host defense activity
Standard
40 amino acids
C189H273N53O56S7
Standard
GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY
4407.97 Da
7.77
0.87
0.47
0.0218
-0.69
0.36
-0.02
13.82
19.50
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1752.07
-19.15
65.0
66.0
143.0
305.0
10.0
42.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0219200
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pseudoplectania nigrella [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
It is the first fungal defensin identified in the secretome of the ascomycete P. nigrella. Chemical modification: three disulfide bonds: C4-C30, C15-C37, and C19-C39
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
Streptococcus pyogenes ESSP 12 strains
0.063-0.5 μg/mL
MIC
Unspecified 61 h
RECORD: Rec_0266570
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pseudoplectania nigrella [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
It is the first fungal defensin identified in the secretome of the ascomycete P. nigrella. Chemical modification: three disulfide bonds: C4-C30, C15-C37, and C19-C39
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
Staphylococcus epidermidis MSSE
8-32 μg/mL
MIC
Unspecified 61 h
RECORD: Rec_0270843
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pseudoplectania nigrella [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
It is the first fungal defensin identified in the secretome of the ascomycete P. nigrella. Chemical modification: three disulfide bonds: C4-C30, C15-C37, and C19-C39
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
S. pneumoniae PSSP 109 strains
0.25-8 μg/mL
MIC
Unspecified 61 h
RECORD: Rec_0296916
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pseudoplectania nigrella [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
It is the first fungal defensin identified in the secretome of the ascomycete P. nigrella. Chemical modification: three disulfide bonds: C4-C30, C15-C37, and C19-C39
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
Staphylococcus aureus MRSA 4 strains
16-32 μg/mL
MIC
Unspecified 61 h
RECORD: Rec_0298704
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pseudoplectania nigrella [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
It is the first fungal defensin identified in the secretome of the ascomycete P. nigrella. Chemical modification: three disulfide bonds: C4-C30, C15-C37, and C19-C39
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
S. pneumoniae PRSP 24 strains
0.125-4 μg/mL
MIC
Unspecified 61 h
Showing 5 records on this page · Page 3 of 5