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MYP_089364
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
40 amino acids
C189H273N53O56S7
Standard
Sequence
GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4407.97 Da
7.77
0.87
0.47
0.0218
-0.69
0.36
-0.02
13.82
19.50
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1752.07
-19.15
65.0
66.0
143.0
305.0
10.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019020 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0030378 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pseudoplectania nigrella [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
It is the first fungal defensin identified in the secretome of the ascomycete P. nigrella. Chemical modification: three disulfide bonds: C4-C30, C15-C37, and C19-C39
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
C. diphtheriae 4 strains
2-8 μg/mL
MIC
Unspecified 61 h
PaperPlectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus
RECORD: Rec_0051856 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0058593 VERIFIED: NO
Provenance & Taxonomy
Pseudoplectania nigrella [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae
RECORD: Rec_0098127 VERIFIED: YES
Provenance & Taxonomy
Pseudoplectania nigrella [Fungus]
Defensin
96584
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-30, 15-37, 19-39
Bio-Activity Profile
Antibacterial
PaperPlectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus PMID16222292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16222292/
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