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MYP_089338
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Basic Information
Kassinatuerin-2Md (Frogs, amphibians, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C96H159N25O24
Standard
Sequence
IIGAIAAALPHVINAIKNTF
Physicochemical Analysis
2047.44 Da
8.76
0.85
0.59
0.0423
1.27
0.55
0.52
12.56
156.50
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
768.54
-4.75
25.0
26.0
64.0
145.0
3.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0059137 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
PaperPubMed PMID: 19427345 PMID19427345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19427345/
RECORD: Rec_0089879 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 70.0%, E 0.0%, T 10.0%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0110534 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPubMed PMID: 19427345 PMID19427345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19427345/
RECORD: Rec_0110772 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic Anti-Gram-positive Cytotoxic
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0142869 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Kasseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
120.0 μM
HC50
PaperL. Wang et al. / Peptides 30 (2009) 1428-1433. A family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata Evidence URLhttps://www.uniprot.org/uniprotkb/C7C1L1/entry
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