Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC554H883N147O166S3

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVSAVEFPSASISLIPGTGIKLVIGNASLIINMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPLDNTGHTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12355.02 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.12

Net Charge (pH 7.4) 3.93

Charge Density (pH 7.0) 0.0362

GRAVY Index0.09

Hydrophobic Moment 0.53

Boman Index0.14

Instability Index16.15

Aliphatic Index 96.58

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5022.43

LogP -55.26

H-bond Donors 180.0

H-bond Acceptors 175.0

Rotatable Bonds 408.0

Heavy Atoms 870.0

Ring Count 18.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041265 VERIFIED: NO

Provenance & Taxonomy

OrganismFregata magnificens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria