Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC428H687N141O125S11

DescriptionStandard

        MAHDRCSERNDRQREGERERELKMRTLELMLITLLLFTASQANEAEVLGWTCGYRGLCRRHCNAQEYMIGYHGCPRRYRCCALRY
    

Molecular Weight10160.62 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.22

Charge Density (pH 7.0) 0.0437

GRAVY Index-0.73

Hydrophobic Moment 0.62

Boman Index-0.27

Instability Index35.86

Aliphatic Index 65.53

Aromaticity 0.0824

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4384.75

LogP -44.65

H-bond Donors 167.0

H-bond Acceptors 143.0

Rotatable Bonds 344.0

Heavy Atoms 705.0

Ring Count 12.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238913 VERIFIED: NO

Provenance & Taxonomy

OrganismDanionella translucida [Bacterium]

FamilyDefensin

Tax ID623744

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence