Peptide Database

Peptide NameDOTA10-AngioPep (DOTA-AP)

Function Ontology

Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC104H149N29O31

DescriptionStandard

        TFFYGGSRGKRNNFKTEEY
    

Molecular Weight2301.47 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.40

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0737

GRAVY Index-1.49

Hydrophobic Moment 0.52

Boman Index-0.31

Instability Index71.48

Aliphatic Index 0.00

Aromaticity 0.2632

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1024.89

LogP -11.34

H-bond Donors 37.0

H-bond Acceptors 33.0

Rotatable Bonds 76.0

Heavy Atoms 164.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041948 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAngiopep

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermSource entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata

Other ModsConjugate type: amide; Conjugated small molecule: 6-Maleimidocaproic acid derivative linker

Bio-Activity Profile

Function

Imaging

RECORD: Rec_0055048 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 36.8%, C 63.2% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Drug Delivery Vehicle Blood-Brain Barrier

RECORD: Rec_0198229 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

Bio-Activity Profile

Function

-

RECORD: Rec_0253298 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAngiopep

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermSource entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata

Other ModsConjugate type: amide; Conjugated small molecule: Fallypride derivative

Bio-Activity Profile

Function

Imaging