Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1338H2098N340O391S5

DescriptionStandard

        MEKPILKNLNEMLCPIIASEVKALNANLSTLEVLTKIDNYTLLDYSLISSPEITENYLDLNLKGVFYPLENLTDPPFSPVPFVLPERSNSMLYIGITEYFFKSASFAHFTAGAFNVTLSTEEISNHFVQNSQGLGNVLSRVASTSVGLVILGQRLVCSLSLNRFRLALPESNRSNIEVLRFENILSSILHFGILPLANAKLQQGFPLPNPHKISFINSDIEVLEGFLLISTDLKYETSSKQQPSFHGWEGLNLISGQWRGKSAP
    

Molecular Weight29363.34 Da

Isoelectric Point (pI)5.57

Net Charge (pH 7.0)-5.04

Net Charge (pH 7.4) -5.60

Charge Density (pH 7.0) -0.0191

GRAVY Index0.07

Hydrophobic Moment 0.63

Boman Index0.14

Instability Index48.09

Aliphatic Index 107.08

Aromaticity 0.0947

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171806 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence