Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC418H679N119O117S9

DescriptionStandard

        MKLLLLVFAALGFLVTPASGGWTGCTGNLPGHCKVQCSSLERAMFMCDRYRPCCVRDSSIPVPPPVQINKPSTKREKERPGEVLLNN
    

Molecular Weight9532.17 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.54

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0521

GRAVY Index-0.07

Hydrophobic Moment 0.54

Boman Index0.03

Instability Index38.01

Aliphatic Index 81.72

Aromaticity 0.0575

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3737.65

LogP -37.36

H-bond Donors 133.0

H-bond Acceptors 132.0

Rotatable Bonds 306.0

Heavy Atoms 663.0

Ring Count 16.0

Amide Bonds 92.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0254862 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus asinus asinus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence

RECORD: Rec_0341466 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence