Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC435H719N123O116S11

DescriptionStandard

        MKLLLFLLILLAMEPVVSAECWMNGHCRLVCKSDEDSLIRCSNRKRCCVLSRYLTVQPMTVERIQPWTVPPMSKIKPKGNINGYRG
    

Molecular Weight9880.83 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0760

GRAVY Index0.02

Hydrophobic Moment 0.54

Boman Index0.00

Instability Index37.73

Aliphatic Index 98.49

Aromaticity 0.0581

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3838.63

LogP -31.41

H-bond Donors 140.0

H-bond Acceptors 135.0

Rotatable Bonds 328.0

Heavy Atoms 685.0

Ring Count 14.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142775 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence