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MYP_089198
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Basic Information
Gaegurin-5 (1-13)[K7,11H;V8A;A9L;,V12L], PTP-7c
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C71H107N17O15
Standard
Sequence
FLGALFHALSHLL
Physicochemical Analysis
1438.71 Da
6.92
-0.07
-0.37
-0.0050
1.58
0.37
0.65
2.70
165.38
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
490.11
-0.47
17.0
17.0
44.0
103.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0150066 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
8 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0150169 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MCF-10A
120 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0152475 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung carcinoma A549
42
IC50
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0154597 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 0% Hemolysis=30 μM
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0184387 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhimurium
64 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
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