Peptide Database

Peptide NameConotoxin A3

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC130H198N38O36S6

DescriptionStandard

        CTPRHGVCFYSYFCCSKACNPSSKRCL
    

Molecular Weight3061.59 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)3.78

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.1401

GRAVY Index-0.12

Hydrophobic Moment 0.41

Boman Index-0.07

Instability Index82.96

Aliphatic Index 28.89

Aromaticity 0.1481

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1191.56

LogP -14.69

H-bond Donors 49.0

H-bond Acceptors 47.0

Rotatable Bonds 93.0

Heavy Atoms 210.0

Ring Count 7.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267847 VERIFIED: NO

Provenance & Taxonomy

OrganismConus abbreviatus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0314397 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic