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MYP_089116
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
2 amino acids
C15H23N3O4
Standard
Sequence
YK
Physicochemical Analysis
309.36 Da
8.59
0.76
0.55
0.3790
-2.60
0.78
-0.62
5.00
0.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
138.67
-0.04
5.0
5.0
9.0
22.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0090053 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Toxic
PaperOtani H., Suzuki H.. Isolation and characterization of cytotoxic small peptides, alpha-casecidins, from bovine alphas1-casein digested with bovine trypsin. Anim. Sci. J., 74, 427-435, 2003.
RECORD: Rec_0110335 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
610.0
IC50
PaperMeisel H., Walsh D. J., Murray B., FitzGerald R. J.. ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315, 2006.
RECORD: Rec_0187768 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Enkephalin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-III Inhibitory
Dipeptidyl peptidase III
PaperLee, C.M.; Snyder, S.H.. Dipeptidylaminopeptidase-III of rat brain selective affinity for enkephalin and angiotensin. J. Biol. Chem., 257, 12043-12050, 1982.
RECORD: Rec_0228054 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperOtani H., Suzuki H.. Isolation and characterization of cytotoxic small peptides, alpha-casecidins, from bovine alphas1-casein digested with bovine trypsin. Anim. Sci. J., 74, 427-435, 2003.
RECORD: Rec_0337982 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAnimal and Plant Proteins as Precursors of Peptides with ACE Inhibitory Activity – An in silico Strategy of Protein Evaluation
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