Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC924H1408N216O285S6

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFRPFIDLDLKGVVFPAGNYTDSPYVAASFTIPDQSNSMLHLAFSEYFFQTSSFAYYTAGAFNRTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIINLEQDSFTVEIQGSGEVLAVLPDSTTQSLFTLNIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight20294.73 Da

Isoelectric Point (pI)4.08

Net Charge (pH 7.0)-13.15

Net Charge (pH 7.4) -13.47

Charge Density (pH 7.0) -0.0714

GRAVY Index0.23

Hydrophobic Moment 0.60

Boman Index0.21

Instability Index44.24

Aliphatic Index 95.43

Aromaticity 0.1250

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7967.60

LogP -88.88

H-bond Donors 271.0

H-bond Acceptors 279.0

Rotatable Bonds 649.0

Heavy Atoms 1431.0

Ring Count 34.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017386 VERIFIED: NO

Provenance & Taxonomy

OrganismCallaeas wilsoni [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria