Peptide Database

Peptide NameNatriuretic peptide HsNP-b

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC159H255N47O47S2

DescriptionStandard

        SDPKIGNGCFGFPIDRIGSVSGLGCNRLVQNPPKP
    

Molecular Weight3641.14 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0412

GRAVY Index-0.30

Hydrophobic Moment 0.62

Boman Index0.04

Instability Index6.44

Aliphatic Index 72.29

Aromaticity 0.0571

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1492.26

LogP -18.31

H-bond Donors 50.0

H-bond Acceptors 51.0

Rotatable Bonds 114.0

Heavy Atoms 255.0

Ring Count 7.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020627 VERIFIED: YES

Provenance & Taxonomy

OrganismHoplocephalus stephensii [Animal]

FamilyNatriuretic peptide HsNP

Tax ID196418

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0059018 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudechis australis [Animal]

FamilyNatriuretic peptide PaNP

Tax ID8670

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0137220 VERIFIED: YES

Provenance & Taxonomy

OrganismOxyuranus microlepidotus [Animal]

FamilyNatriuretic peptide OmNP

Tax ID111177

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0352175 VERIFIED: YES

Provenance & Taxonomy

OrganismOxyuranus scutellatus scutellatus [Animal]

FamilyNatriuretic peptide OsNP

Tax ID8667

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour