Peptide Database

Peptide Nameprotegrin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC770H1243N211O227S7

DescriptionStandard

        METQRASLSTCRWSLWLLLLGLAVPWASAQALSYREAVLRAVDRLNEQSSDPNLYRLLELDLPPKADEDPDTPKPVSFMVKETVCPRRTQQPPEQCDFKENGVVKQCLGTVTLDQITGQLAVTCDELQSVGLGRIVRKAIKYVPTVIRIASWFL
    

Molecular Weight17312.84 Da

Isoelectric Point (pI)6.30

Net Charge (pH 7.0)-0.52

Net Charge (pH 7.4) -0.85

Charge Density (pH 7.0) -0.0034

GRAVY Index-0.14

Hydrophobic Moment 0.91

Boman Index-0.00

Instability Index35.01

Aliphatic Index 99.35

Aromaticity 0.0649

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7041.99

LogP -64.98

H-bond Donors 247.0

H-bond Acceptors 234.0

Rotatable Bonds 566.0

Heavy Atoms 1215.0

Ring Count 25.0

Amide Bonds 166.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0358487 VERIFIED: NO

Provenance & Taxonomy

OrganismCamelus ferus [Animal]

FamilyCathelicidin

Tax ID419612

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal