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MYP_089064
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Basic Information
TatP59W
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C76H134N36O16
Standard
Sequence
GRKKRRQRRRPWQ
Physicochemical Analysis
1808.11 Da
12.00
7.76
7.55
0.5968
-3.44
0.48
-1.42
193.91
0.00
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
929.14
-10.55
36.0
24.0
64.0
128.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0260073 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (5% Hemolysis at >200 microM
200 μM
Hemolysis
PMID19206074 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19206074/
RECORD: Rec_0352173 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Salmonella typhimurium KCTC 1926
2 μM
MIC
PMID19206074 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19206074/
RECORD: Rec_0355104 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis KCTC 1917
2 μM
MIC
PMID19206074 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19206074/
RECORD: Rec_0355788 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labeled with fluorescein
Bio-Activity Profile
Cell-penetrating peptide
V79 cells
Fluorescence-based uptake assay
PMID12849987 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12849987/
RECORD: Rec_0394405 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
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