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MYP_089055
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Basic Information
Antimicrobial peptide PGQ (PGQ; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
24 amino acids
C112H194N30O31
Standard
Sequence
GVLSNVIGYLKKLGTGALNAVLKQ
Physicochemical Analysis
2456.92 Da
10.00
2.76
2.55
0.1148
0.55
0.55
0.26
-5.33
142.08
0.0417
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1000.64
-8.92
34.0
34.0
85.0
173.0
1.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071197 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
250-500 μg/mL
MIC
PMID1717472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1717472/
RECORD: Rec_0121170 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus 29213
250-500
MIC
PaperAntimicrobial peptides in the stomach of Xenopus laevis.
RECORD: Rec_0157235 VERIFIED: YES
Provenance & Taxonomy
African clawed [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID8375398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8375398/
RECORD: Rec_0170092 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
250-500 μg/mL
MIC
PMID1717472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1717472/
RECORD: Rec_0178512 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pneumonae
125-250 μg/mL
MIC
PMID1717472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1717472/
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