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MYP_089050
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Basic Information
Human obestatin
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
23 amino acids
C116H175N31O34
Standard
Sequence
FNAPFDVGIKLSGVQYQQHSQAL
Physicochemical Analysis
2547.82 Da
6.74
-0.15
-0.41
-0.0067
-0.16
0.41
0.14
30.38
84.78
0.1304
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1062.87
-10.75
34.0
35.0
82.0
181.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0101893 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Proghrelin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Mouse kidney membrane homogenate
HPLC, LC-UV/MS
67.7 [61.7, 75.1] min
PaperIn vitro metabolic stability of obestatin: kinetics and identification of cleavage products
RECORD: Rec_0138388 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Proghrelin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Mouse liver homogenate with protease inhibitor cocktail
HPLC, LC-UV/MS
28.0 [25.8, 30.5] min
PaperIn vitro metabolic stability of obestatin: kinetics and identification of cleavage products
RECORD: Rec_0140967 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0169044 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Proghrelin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Mouse plasma
HPLC, LC-UV/MS
65.1 [59.6, 71.7] min
PaperIn vitro metabolic stability of obestatin: kinetics and identification of cleavage products
RECORD: Rec_0171142 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Proghrelin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Mouse liver homogenate
HPLC, LC-UV/MS
13.3 [12.7, 14.0] min
PaperIn vitro metabolic stability of obestatin: kinetics and identification of cleavage products
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