Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC912H1456N252O252S8

DescriptionStandard

        PTPRALPMAREPMLLLAVTDFVANSAAFTYFKAGVLRRNISSDMLPRKFPLQLRTKNMGVFSHQLQEQYQDQPMELHLWARQQPLISCHSDALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITRNRLGGTVRLTGLSVTQVASNVGPVQVKPLETLLKFGLWLFGVPKANSECCP
    

Molecular Weight20239.37 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)7.29

Net Charge (pH 7.4) 6.96

Charge Density (pH 7.0) 0.0398

GRAVY Index0.03

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index44.10

Aliphatic Index 94.81

Aromaticity 0.0765

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8007.03

LogP -93.69

H-bond Donors 276.0

H-bond Acceptors 271.0

Rotatable Bonds 652.0

Heavy Atoms 1424.0

Ring Count 35.0

Amide Bonds 201.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0018322 VERIFIED: NO

Provenance & Taxonomy

OrganismSakesphorus luctuosus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria