Peptide Database

Peptide NameRanibizumab

Function Ontology

Monoclonal antibody Hematopoietic

Standard StatusStandard

Sequence Length207 amino acids

Chemical FormulaC1002H1537N263O324S4

DescriptionStandard

        SASQDISNYLNWYQQKPGKAPKVLIYFTSSLHSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECEVQLVESGGGLVQPGG
    

Molecular Weight22579.75 Da

Isoelectric Point (pI)5.91

Net Charge (pH 7.0)-2.30

Net Charge (pH 7.4) -2.78

Charge Density (pH 7.0) -0.0111

GRAVY Index-0.45

Hydrophobic Moment 0.58

Boman Index0.01

Instability Index50.01

Aliphatic Index 66.33

Aromaticity 0.1063

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31650.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0272219 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Escherichia coli [Bacterium]

FamilyFab fragment

Tax ID9606;562

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Monoclonal antibody Hematopoietic

Half-Lifeapprox. 9 d.

PaperPubMed-linked source references: PMID:25631483; PMID:25627091; PMID:18054637; PMID:18046235; PMID:18035187; PMID:15671306; PMID:17687925; PMID:25646034; PMID:23560774 PMID25631483;25627091;18054637;18046235;18035187;15671306;17687925;25646034;23560774 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25631483/ PatentCA2286330