Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length500 amino acids

Chemical FormulaC2359H3658N648O725S14

DescriptionStandard

        MARALVCLGDKTTYGAVLSASSSCYEGNRALALTGDMASCSKCGGVYQIIGTVFDMSEDGKAFVATGDRVLCGCPNNVVFGSTTQYVSPAGEAFSQNAPTETAALKTAAPVSPSAPPVAPVLVFAKSGERGAGNTEAGTTDESHYNFGHLSFGTPAQLETAKPEPEQHAQAAKRKPASGSQKPDTGLPWYKRMFGAKPDAPAQAGMPLAIPVATGGGAELAAAGMNALRGLSHFVGSGAVFVNPVTVGVVGTFYSSKLNAGEDDILADSQLAVLAGKSAPTRIRFQWVNDNYGRLKPVAYHTGADSGLDRVRVRSMERNRFTGNYEFWADGADKPTIVWTPDEVEFKAPANTGNRDEPYLPSTITVLPLPSAGEVGSTSTSLPIPDEKSFDDYILVNLPHGMPPIYIYLSNDHKYYTPPKGTPPLAAFPDAKKAVSKTPIKGGGKLRYRWKDSKSRIYEWDSQHGTVEVYDKSGRNHLGEFDPVTGKQTKPADPTRKVEK
    

Molecular Weight53145.10 Da

Isoelectric Point (pI)7.60

Net Charge (pH 7.0)1.27

Net Charge (pH 7.4) 0.38

Charge Density (pH 7.0) 0.0025

GRAVY Index-0.38

Hydrophobic Moment 0.59

Boman Index0.03

Instability Index32.45

Aliphatic Index 66.40

Aromaticity 0.0860

Extinction Coeff. Reduced 61310.00

Extinction Coeff. Oxidized 61685.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226911 VERIFIED: YES

Provenance & Taxonomy

OrganismRahnella sp. ERMR1:05 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)