Peptide Database

Peptide NameDefensin MGD1(25-33) peptide D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Antiviral

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC45H76N18O10S2

DescriptionStandard

        CGGWKRKRC
    

Molecular Weight1093.33 Da

Isoelectric Point (pI)10.11

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.4154

GRAVY Index-1.50

Hydrophobic Moment 0.09

Boman Index-0.63

Instability Index108.76

Aliphatic Index 0.00

Aromaticity 0.1111

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 487.75

LogP -5.09

H-bond Donors 21.0

H-bond Acceptors 16.0

Rotatable Bonds 37.0

Heavy Atoms 75.0

Ring Count 2.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020218 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetTrypanosoma brucei Antat1.1

Activity4 μM

MethodLD50

RECORD: Rec_0106901 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetLeishmania major

Activity12 μM

MethodLD50

RECORD: Rec_0121073 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetHuman cervical carcinoma HeLa MAGIC-5

RECORD: Rec_0212943 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetMicrococcus luteus ATCC 4698

Activity0.8 μM

MethodMIC

RECORD: Rec_0290885 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetHIV-1