Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC355H570N88O99S4

DescriptionStandard

        MDLFNSIVEIAGTFKVSTDTSTKVYDAVMAGVDAWGVLSILAAATGPLAIGGAVLFYMIRKKVKSMGRSVAIAW
    

Molecular Weight7783.11 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0203

GRAVY Index0.72

Hydrophobic Moment 0.70

Boman Index0.31

Instability Index22.62

Aliphatic Index 108.11

Aromaticity 0.0946

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2956.89

LogP -23.90

H-bond Donors 106.0

H-bond Acceptors 105.0

Rotatable Bonds 255.0

Heavy Atoms 546.0

Ring Count 10.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353359 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. larvae [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal