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MYP_088646
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Basic Information
12-(Lys)4-12
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
4 amino acids
C24H50N8O5
Standard
Sequence
KKKK
Physicochemical Analysis
530.70 Da
10.48
3.76
3.55
0.9390
-3.90
0.17
-1.50
7.50
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
254.70
-1.63
9.0
9.0
23.0
37.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0412299 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
branching lysine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa strain PAO1
4 μg/mL
MIC
PMID29767453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29767453/
RECORD: Rec_0413191 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 33592
512 μg/mL
MIC
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
RECORD: Rec_0414644 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human cervical carcinoma HeLa 10-20% Killing
64 μM
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
RECORD: Rec_0418427 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Aspergillus niger ATCC 16404
2000 μg/mL
MIC
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
RECORD: Rec_0419685 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperConoServer: updated content, knowledge, and discovery tools in the conopeptide database PMID22058133 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22058133/
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