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MYP_088646
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Basic Information
12-(Lys)4-12
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
4 amino acids
C24H50N8O5
Standard
Sequence
KKKK
Physicochemical Analysis
530.70 Da
10.48
3.76
3.55
0.9390
-3.90
0.17
-1.50
7.50
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
254.70
-1.63
9.0
9.0
23.0
37.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0403523 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida tropicalis PCM 2681
512 μg/mL
MFC
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
RECORD: Rec_0404096 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human breast adenocarcinoma MDA-MB-231 50% Cell death >30 microM
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
RECORD: Rec_0405998 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human keratinocytes HaCaT
23.5±1.3 μg/mL
IC50
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
RECORD: Rec_0406737 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis ATCC 29212
16 μg/mL
MBC
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
RECORD: Rec_0411615 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli D21
6.25 μM
MIC
PMID22006001;28203232;19237652;27486068;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22006001/
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