Peptide Database

Peptide NameToxin HpTx3

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC155H226N42O46S6

DescriptionStandard

        ECGTLFSGCSTHADCCEGFICKLWCRYERTW
    

Molecular Weight3606.10 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-1.13

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0365

GRAVY Index-0.12

Hydrophobic Moment 0.71

Boman Index0.03

Instability Index13.56

Aliphatic Index 40.97

Aromaticity 0.1613

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1416.98

LogP -13.73

H-bond Donors 58.0

H-bond Acceptors 52.0

Rotatable Bonds 113.0

Heavy Atoms 249.0

Ring Count 8.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052094 VERIFIED: NO

Provenance & Taxonomy

OrganismHeteropoda venatoria [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-16; 9-21; 15-25

Bio-Activity Profile

Function

Toxin

TargetKv4

RECORD: Rec_0244036 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic