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MYP_088604
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Basic Information
HALO-P8
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
26 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KKALLXHPLHXLALLAXHLAHXLKKA
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0215438 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida albicans
50 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0218332 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Pseudomonas aeruginosa
4.2 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0228879 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
O=ornithine
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial Histidine-Rich Amphipathic Cationic Peptides
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0255121 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Plasmodium falciparum
17 μM
IC50
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0271350 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
O=Ornithine
Bio-Activity Profile
Antimicrobial Antiparasitic Toxic Antiplasmodial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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