Peptide Database

Peptide NameA8Δ71-73

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC334H555N101O101S6

DescriptionStandard

        TLQKKIEEIAAKYKHSVVKKCCYDGAAVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISFKRS
    

Molecular Weight7793.99 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)5.43

Net Charge (pH 7.4) 5.08

Charge Density (pH 7.0) 0.0776

GRAVY Index-0.31

Hydrophobic Moment 0.62

Boman Index-0.14

Instability Index57.73

Aliphatic Index 78.14

Aromaticity 0.0571

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3330.71

LogP -37.48

H-bond Donors 123.0

H-bond Acceptors 114.0

Rotatable Bonds 269.0

Heavy Atoms 542.0

Ring Count 6.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414151 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Chemotactic Immunomodulatory Signaling peptide

TargetC5a1 receptor (Mouse); C5a2 receptor (Mouse)

Activity27 nM

MethodIC50