Peptide Database

Peptide NameTrp-8 progonadoliberin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC346H527N99O105S

DescriptionStandard

        QHWSYGLWPGGKREVEGLQESYSEVPNEVSFTDPQHFERSIPQNRISLVREALMNWLEGENTRKKI
    

Molecular Weight7785.55 Da

Isoelectric Point (pI)5.61

Net Charge (pH 7.0)-2.04

Net Charge (pH 7.4) -2.37

Charge Density (pH 7.0) -0.0310

GRAVY Index-0.98

Hydrophobic Moment 0.54

Boman Index-0.15

Instability Index40.92

Aliphatic Index 66.36

Aromaticity 0.1061

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3331.97

LogP -32.42

H-bond Donors 114.0

H-bond Acceptors 106.0

Rotatable Bonds 257.0

Heavy Atoms 551.0

Ring Count 16.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346283 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyTrp-8 progonadoliberin

Tax ID71582

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour