Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC548H869N145O167S3

DescriptionStandard

        PDLNGYEKFGLGNVKYNISGIHVAAVEFPSASISLIPGTGIKLVIGNASLTINMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPQDNTGHTSISLTSCRTTSGDIDIKLTGKS
    

Molecular Weight12256.83 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.04

Hydrophobic Moment 0.48

Boman Index0.15

Instability Index16.35

Aliphatic Index 90.61

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5003.62

LogP -56.92

H-bond Donors 178.0

H-bond Acceptors 175.0

Rotatable Bonds 403.0

Heavy Atoms 863.0

Ring Count 18.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296245 VERIFIED: NO

Provenance & Taxonomy

OrganismRhynochetos jubatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria