Peptide Database

Peptide NamePhylloseptin-B1 (PLS-B1) (Dermaseptin PBN1) (DRP-PBN1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC337H542N84O102S2

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRETEEKEYDQGEDDKSEEKRFLSLIPHIVSGVAALAKHLG
    

Molecular Weight7466.54 Da

Isoelectric Point (pI)5.07

Net Charge (pH 7.0)-4.31

Net Charge (pH 7.4) -4.67

Charge Density (pH 7.0) -0.0653

GRAVY Index-0.10

Hydrophobic Moment 0.67

Boman Index0.03

Instability Index54.92

Aliphatic Index 106.36

Aromaticity 0.0758

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2999.16

LogP -22.07

H-bond Donors 104.0

H-bond Acceptors 102.0

Rotatable Bonds 262.0

Heavy Atoms 525.0

Ring Count 8.0

Amide Bonds 66.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0154032 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermaseptin; Phylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-positive Synergistic peptide Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0386732 VERIFIED: YES