Peptide Database

Peptide NameProtegrin-2 (PG-2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length147 amino acids

Chemical FormulaC717H1169N209O215S10

DescriptionStandard

        METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEVQGVRGGRLCYCRRRFCICVG
    

Molecular Weight16477.87 Da

Isoelectric Point (pI)8.08

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.06

Charge Density (pH 7.0) 0.0098

GRAVY Index-0.28

Hydrophobic Moment 0.77

Boman Index-0.09

Instability Index38.48

Aliphatic Index 90.14

Aromaticity 0.0544

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6842.38

LogP -69.82

H-bond Donors 245.0

H-bond Acceptors 227.0

Rotatable Bonds 541.0

Heavy Atoms 1151.0

Ring Count 21.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149650 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetListeria monocytogenes

RECORD: Rec_0265490 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli

RECORD: Rec_0413798 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans