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MYP_088538
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Basic Information
Lactomodulin
Antimicrobial
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
52 amino acids
C249H398N66O73S
Standard
Sequence
MNKLNEVELSKISGGIGPLVIPVAAILGFLATDAWNHADELVAGVKQGWERS
Physicochemical Analysis
5516.29 Da
5.00
-2.40
-2.68
-0.0462
0.24
0.50
0.22
34.25
114.42
0.0577
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2207.14
-18.50
74.0
73.0
182.0
389.0
8.0
55.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095951 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus rhamnosus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
E. faecium anti-VRE BAA 2317
1.2 μM
MIC
PaperDiscovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens.
RECORD: Rec_0195467 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus rhamnosus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
C. difficile ATCC 43602
1.1 μM
MIC
PaperDiscovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens.
RECORD: Rec_0320728 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus rhamnosus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Staphylococcus aureus ATCC 25923 or MRSA BAA 2313
0.8-1.4 μM
MIC
PaperDiscovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens.
RECORD: Rec_0356523 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus rhamnosus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Escherichia coli ATCC 33694
7.5 μM
MIC
PaperDiscovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens.
RECORD: Rec_0369423 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus rhamnosus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Listeria monocytogenes ATCC 15313
1.2 μM
MIC
PaperDiscovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens.