Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC132H203N39O38S2

DescriptionStandard

        SANSSPLAARERKAGCKNFFWKTFTSC
    

Molecular Weight3008.39 Da

Isoelectric Point (pI)9.85

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.1274

GRAVY Index-0.53

Hydrophobic Moment 0.35

Boman Index-0.13

Instability Index44.11

Aliphatic Index 29.26

Aromaticity 0.1481

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1273.64

LogP -16.16

H-bond Donors 48.0

H-bond Acceptors 44.0

Rotatable Bonds 97.0

Heavy Atoms 211.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056594 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0147524 VERIFIED: NO

Provenance & Taxonomy

OrganismProtopterus annectens [Animal]

FamilySomatostatin

Tax ID7888

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide16-27

Bio-Activity Profile

Function

Hormone Inhibitory neuropeptide

RECORD: Rec_0399580 VERIFIED: YES

Provenance & Taxonomy

OrganismProtopterus annectens [Animal]

FamilySomatostatin

Tax ID7888

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide16-27

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeExperimental: 2.8±0.3 minute; /168 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour