Peptide Database

Peptide NameFPA-Bombinin-BO (toads, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC106H176N30O30

DescriptionStandard

        GIGGALLSAKAALGLAKGLAEHFAN
    

Molecular Weight2350.71 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0339

GRAVY Index0.72

Hydrophobic Moment 0.46

Boman Index0.38

Instability Index-2.82

Aliphatic Index 121.60

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 943.06

LogP -9.19

H-bond Donors 32.0

H-bond Acceptors 32.0

Rotatable Bonds 79.0

Heavy Atoms 166.0

Ring Count 2.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194966 VERIFIED: YES

Provenance & Taxonomy

OrganismAsian bombinid [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

Targethorse red blood cells

RECORD: Rec_0235389 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity3 μM

MethodMIC

RECORD: Rec_0268981 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity12 μM

MethodMIC

RECORD: Rec_0285410 VERIFIED: YES

Provenance & Taxonomy

OrganismAsian bombinid [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCandida albicans

Activity7 μM

MethodMIC

RECORD: Rec_0372114 VERIFIED: YES

Provenance & Taxonomy

OrganismAsian bombinid [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEscherichia coli

Activity14 μM

MethodMIC

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